For do that, first you should enables concurrent execution of agents with:
DominoAsyncrhonizeAgents = 1
ODBCThreadSafeDrivers = ALL
on the NOTES.ini.
Then, activate connection pooling for LS:DO with NOTES.ini variable:
ODBCConnectionPooling = 1
And activate in the ODBC Administrator (please check the last version of ODBC
administrator for this feature).
Use NT perfomance monitor to track pool statics.