How can I stop spoofed e-mails without enabling reverse DNS?
If you send an e-mail in the format "email@example.com"@mydomain.com there seem to be no inbound or outbound controls that identify this as an invalid format, and the mail is relayed by the server in mydomain to Hotmail.
Enabling reverse DNS is not a practical solution because so many do not have these records set up, and enabling it will block a great deal of legitimate mail.
Are you sure? In my experience, the "anti-relay" controls in Domino work quite well. I have successfully shut off relaying on many Domino mail servers for my customers. In R6, see names.nsf -> Configuration -> Servers -> Configurations -> <your server> -> Router -> Restrictions -> SMTP Inbound Controls.
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